Radiotherapy | Oncology: RAD 551

oncology

Table of Contents

Radiation Beam Measurement and Isodose Curves in Radiotherapy

1. Radiation Beam Measurement

Radiation beam measurement is essential in radiotherapy to ensure accurate dose delivery to cancerous tissues while minimizing exposure to healthy tissues. Dosimetry, ionization chambers, and other measurement devices are used to measure radiation doses precisely.

1.1 Dosimetry

Dosimetry is the measurement of absorbed radiation doses in a medium (e.g., human tissue, water phantom). It ensures that patients receive the correct dose during treatment.

Types of Dosimetry

  • Absolute Dosimetry: Determines the exact dose delivered.
  • Relative Dosimetry: Compares dose distributions in different conditions.
  • In Vivo Dosimetry: Direct measurement on the patient’s body during treatment.

1.2 Ionization Chambers

Ionization chambers are gas-filled detectors that measure radiation doses by collecting ionized particles.

Principle of Operation

  1. Radiation ionizes gas molecules inside the chamber.
  2. The collected charge is converted into an electrical signal.
  3. The signal is proportional to the radiation dose received.

Types of Ionization Chambers

TypeApplication
Parallel-plate chamberSurface dose measurements
Cylindrical chamberRoutine radiation beam calibration
Well-type chamberBrachytherapy source measurements

1.3 Other Measurement Devices

Apart from ionization chambers, other devices are used for dosimetry:

DeviceFunction
Thermoluminescent Dosimeters (TLDs)Absorb radiation and release stored energy as light
Silicon DiodesSemiconductor-based real-time radiation detection
Film DosimetryUses radiographic film to measure 2D dose distribution
Optically Stimulated Luminescence Dosimeters (OSLDs)Detects radiation exposure through optical stimulation

2. Isodose Curves

2.1 Definition of Isodose Curves

Isodose curves are contour lines that represent equal radiation dose levels within a treated volume. They help visualize how radiation is distributed in the patient’s body.

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Image: Sample Isodose Curves for a Radiation Beam
(A diagram showing isodose curves over a tumor and surrounding tissue.)

2.2 Interpretation of Isodose Curves

  • Lines closer togetherSteeper dose gradient (sharp dose fall-off).
  • Lines spread apartMore uniform dose distribution.
  • 100% Isodose LinePrescribed tumor dose.
  • 50% Isodose LineHalf of the prescribed dose area.

2.3 Clinical Significance of Isodose Curves

  • Treatment Planning: Helps determine optimal radiation angles.
  • Dose Homogeneity: Ensures uniform tumor coverage.
  • Organ Sparing: Minimizes radiation exposure to healthy tissues.
  • Verification of Treatment: Confirms the correct dose delivery.

3. Conclusion

  • Dosimetry and measurement devices ensure accurate radiation dose delivery.
  • Ionization chambers, TLDs, and diodes help in radiation monitoring.
  • Isodose curves provide a visual representation of radiation dose distribution for optimal treatment planning.

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